Sickle Cell Anemia: Types, Symptoms, and Treatment
Fetal And Neonatal Brain Injury
Table of Contents1. Neonatal encephalopathy2. Mechanisms of neurodegeneration and therapeutics in animal modes of neonatal hypoxic-ischemic encephalophathy3. Cellular and molecular biology of hypoxic-encephalopathy4. The pathogenesis of preterm brain injury5. Prematurity and complications of labor and delivery6. Risks and complications of multiple gestations7. Intrauterine growth restriction8. Maternal diseases that affect fetal development9. Obstetrical conditions and practices that affect the fetus and newborn10. Fetal and neonatal injury as a consequence of maternal substance abuse11. Pregnancy induced hypertension, HELLP syndrome and chronic hypertension12. Complications of labor and delivery13. Fetal response to asphyxia14. Antepartum evaluation of fetal well-being15. Intrapartum evaluation of the fetus16. Clinical manifestations of hypoxic-ischemic encephalopathy17. The use of EEG in assessing acute and chronic brain damage in the newborn18. Neuroimaging in the evaluation of pattern and timing of fetal and neonatal brain abnormalities19. Light-based functional assessment of the brain20. Placental pathology and the etiology of fetal and neonatal brain injury21. Correlations of clinical, laboratory, imaging and placental findings as to the timing of asphyxial events22. Congenital malformations of the brain23. Neurogenetic disorders of the brain24. Hemorrhagic lesions of the CNS25. Neonatal stroke26. Hypoglycemia in the neonate27. Hyperbilirubinemia and kernicterus28. Polycythemia and fetal-maternal bleeding29. Hydrops fetalis30. Bacterial sepsis in the neonate31. Neonatal bacterial meningitis32. Neurological sequelae of congenital perinatal infection33. Perinatal human immunodeficiency virus infection34. Inborn errors of metabolism with features of HIE35. Acidosis and alkalosis36. Meconium staining and the meconium aspiration syndrome37. Persistent pulmonary hypertension of the newborn38. Pediatric cardiac surgery: relevance to fetal and neonatal brain injury39. Neonatal resuscitation: immediate management40. Improving performance, reducing error, and minimizing risk in the delivery room41. Extended management following resuscitation42. Endogenous and exogenous neuroprotective mechanisms after hypoxic ischemic injury43. Neonatal seizures44. Nutritional support of the asphyxiated infant45. Early childhood neurodevelopmental outcome of preterm infants46. Assessment and management of infants with cerebral palsy47. Long term impact of neonatal events on speech, language development and academic achievement48. Neurocognitive outcomes of term infants with perinatal asphyxia49. Appropriateness of intensive care application50. Medicolegal issues in perinatal brain injury.
Look InsideDavid K. Stevenson, Stanford University School of Medicine, CaliforniaDavid K. Stevenson is Harold K. Faber Professor of Pediatrics and Vice Dean and Senior Associate Dean for Academic Affairs at Stanford University School of Medicine, Stanford, USA.
William E. Benitz, Stanford University School of Medicine, CaliforniaWilliam E. Benitz is the Philip Sunshine Professor of Pediatrics and Chief, Division of Neonatal and Developmental Medicine at Stanford University School of Medicine, Stanford, USA.
Philip Sunshine, Stanford University School of Medicine, CaliforniaPhilip Sunshine is Professor of Pediatrics (Emeritus) at Stanford University School of Medicine, Stanford, USA.
Susan R. Hintz, Stanford University School of Medicine, CaliforniaSusan R. Hintz is Associate Professor of Pediatrics at Stanford University School of Medicine, Stanford, USA.
Maurice L. Druzin, Stanford University School of Medicine, CaliforniaMaurice L. Druzin is Charles B. And Ann L. Johnson Professor and Professor and Vice Chair, Department of Obstetrics and Gynecology and Chief, Division of Maternal Fetal Medicine at Stanford University School of Medicine, Stanford, USA.
ContributorsPhilip Sunshine, Lee J. Martin, Zinaida S. Vexler, Donna M. Ferriero, Janet Shimotake, Laura Bennet, Justin Mark Dean, Alistair J. Gunn, Yasser Y. El-Sayed, Maurice L. Druzin, Justin Collingham, Amen Ness, Yair Blumenfeld, Usha Chitkara, Alistair G. S. Philip, William W. Hay, Jr., David K. Stevenson, Bonnie Dwyer, Justin Collingham, Jane Church, Reinaldo Acosta, H. Eugene Hoyme, Melanie A. Manning, Louis Halamek, Deirdre Lyell, Yair Blumenfeld, Masoud Taslimi, Israel Hendler, Daniel S. Seidman, Jin S. Hahn, Donald M. Lson, Alexis S. Davis, Patrick D. Barnes, Ken Brady, Chandra Ramamoorthy, Theonia Boyd, David K. Stevenson, Ronald J. Wong, William E. Benitz, Jin S. Hahn, Ronald J. Lemire, Jonathan A. Bernstein, Louanne Hudgins, Linda S. De Vries, Hanna C. Glass, Donna M. Ferriero, Staish C. Kalhan, Robert Schwartz, Marvin Cornblath, Ronald J. Wong, Phyllis A. Dennery, Ted S. Rosenkrantz, Shikha Sarkar, William Oh, David P. Carlton, Hayley A. Gans, Rima Hanna-Wakim, Andrea Enright, Kathleen Gutierrez, Avinash K. Shetty, Yvonne A. Maldonado, Gregory M. Enns, Ronald S. Cohen, Thomas E. Wisewell, William D. Rhine, Krisa P. Van Meurs, Giles J. Peek, Louis P. Halamek, Julie M. R. Arafeh, Robert D. Barrett, Mark S. Scher, John A. Kerner, Trenna L. Sutcliffe, Heidi M. Feldman, Irene M. Loe, Steven P. Miller, Bea Latal, Amnon Goldworth, Ernlé W. D. Young, David Sheuerman
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BiliLux LED Phototherapy Light System From Dräger
The BiliLux is a compact and lightweight LED phototherapy light system for the treatment of neonatal jaundice. It provides superior phototherapy performance, individualized therapy with electronic documentation capabilities and the flexibility for seamless integration into practically every workplace.
BenefitsSuperior phototherapy with even and broad irradiance distribution
Phototherapy is effectively used for treating neonatal hyperbilirubinemia: The BiliLux phototherapy light has its irradiance peaks in the most effective wavelength range to reduce the bilirubin which is 460-490 nm. By achieving extremely high irradiance levels, the BiliLux fullfills the requirements of the American Academy of Prediatrics (AAP). In addition, the irradiance can be dimmed in 5 steps to provide the adequate therapy for the patient. The phototherapy light features a large surface area to cover full term and premature babies. The irradiance is evenly distributed over the entire mattress to ensure superior phototherapy.
Seamless workplace integration for more flexibility
The BiliLux phototherapy light was designed for flexible use and seamless integration into the neonatal workplace. The phototherapy light can be placed on an incubator hood, mounted with the spring arm to warming therapy devices or ceiling supplies or used with a trolley. The BiliLux offers the perfect combination for every workplace. To simplify the process, the phototherapy light can be easily locked and unlocked by using the intuitive and safe quick-connect mechanism.
The BiliLux also features a white observation light to observe the baby between phototherapy sessions or to switch white light on during phototherapy to soften blue light.
Designed for a healthy and family-friendly environment
The family-friendly and compact design saves space around the neonatal workplace while simultaneously providing high irradiances to treat neonatal jaundice. The BiliLux is lightweight for easy handling and storage. And most important: it is soundless to ensure a calm and nuturing atmosphere for the baby, parents and caregivers.
Infection prevention – priority in our development
Hygiene and infection prevention is an important topic in the neonatal segment: the BiliLux was designed for easy and fast cleaning supported by smooth surfaces. Unlike some other phototherapy devices, the BiliLux does not have any ventilation slots or fans in order to improve infection prevention.
Individualized care and quality management – easy and safe
The optional BiliLux Radiometer is specifically designed for the phototherapy light and instantly measures the irradiance. By using the radiometer, the correct positioning of the baby under the phototherapy light and the adequate irradiance that the baby receives can be ensured. In addition, each measurement (incl. Date and time) and the phototherapy duration can be stored and downloaded in a phototherapy report e.G. For patient documentation or quality control purposes.
Electronic data transfer – for more efficient workflows
The phototherapy LED supports the hospital and clinical processes by providing the ability for electronic documentation. The electronic data transfer is much faster and less prone to errors. The work in the NICU becomes more efficient.
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